Editors: Smith , Roy G. In Human Growth Hormone: Research and Clinical Ptractice, Roy Smith and a distinguished panel of researchers and clinicians combine a review of GH regulation and its action at the molecular level with a state-of-the-art description of the basis for GH deficiency and the use of GH therapy in a variety of clinical situations. Also described are a family of GH-secretagogues that bind to a new orphan receptor controlling the physiology of GH release. The discussion of the new GH therapeutics includes their design, their action as regulators in the pituitary gland and in the central nervous system, and their use as new agents for treating growth hormone deficiency states.
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The Growth Hormone Research Society
Please join StudyMode to read the full document. One of its main functions is to increase growth in children and adolescents as they get older. HGH also helps regulate body composition, body fluids, muscle and bone growth , sugar and fat metabolism, and in some aspects, heart function. Human growth hormone can also be produced synthetically. Synthetic human growth hormone was originally created by a pharmaceutical manufacturer in Prior to the development of synthetic HGH, scientists and doctors extracted it from corpses to treat patients that suffered from growth deficiency.
Human Growth Hormone Deficiency
This unprecedented public health emergency has forced people into a prolonged social isolation, with profound impact on their physical, mental and economic health. Governments, institutions and companies are restricting travel and all kind of events have been cancelled worldwide. Considering all these problems, the executive committee of our society have been virtually meeting last week with the Local Organizing Committee and with a great sorrow we have decided to cancel the 10th International Congress of the GRS and IGF Societies, which was scheduled to be held this year in Foz do Iguassu, Brazil, between November. Although this is of great disappointment, it is strongly felt that this decision was taken in the best all round interests of our community, since speakers, sponsors and participants would face many difficulties to organize their travels, attend the congress and enjoy the meeting. Obviously, we will keep our members informed about any further developments.
Short stature remains the most common reason for referral to a pediatric Endocrinologist and its management remains a challenge. One of the main controversies is the diagnosis of idiopathic short stature and the role of new technologies for genetic investigation of children with inadequate growth. Complexities in management of children with short stature includes selection of who should receive interventions such as recombinant human growth hormone, and how should this agent dose be adjusted during treatment. Should anthropometrical data be the primary determinant or should biochemical and genetic data be used to improve growth response and safety? Furthermore, what is considered a suboptimal response to growth hormone therapy and how should this be managed?